Yes. The Town allows a two types of home businesses; a home occupation and home business. Home occupation can be obtained by simply applying for a business license and putting your residence as the physical location.
Home occupations are at the residential scale for small businesses where only the person(s) residing at the residence can be employed. A home business requires a conditional use permit, which requires Town Council approval, and allows a business more in line with what would be allowed in a commercial tenant space.